摘要 |
PROBLEM TO BE SOLVED: To provide an industrially-suitable technology for organ regeneration using an easily-producible induced pluripotent stem cell (iPS cell).SOLUTION: In a blastocyst complementation method, organ regeneration is performed by utilizing a fact that deficiency of an organ such as pancreas or the like is complemented by injecting an induced pluripotent stem cell (iPS cell) into a developed blastocyst. The method uses the iPS cell to manufacture, in a living body of a nonhuman mammal having abnormality not causing development of a target organ at a development stage, the target organ derived from a different individual mammal that is an individual different from the nonhuman mammal. |