| 摘要 |
Provided is a glucoside compound, which is capable of providing a phosphoramidite, which can be produced at a low cost and can produce a nucleic acid in a high yield and with high purity. A glycoside compound represented by the following chemical formula (1). In the chemical formula (1),
B is an atomic group having a nucleic acid base skeleton, and optionally having a protecting group,
R 1 and R 2 are each a hydrogen atom or a protecting group,
or R 1 and R 2 in conjunction optionally form an atomic group represented by the following chemical formula (R 1 R 2 A) or (R 1 R 2 B):
each R 1a is a hydrogen atom, a straight chain or branched alkyl group and the like,
L 1 is an unsubstituted or alkyl-substituted ethylene group,
R 3 is a group represented by the following chemical formula (R 3 ):
in the chemical formula (R 3 ),
n is a positive integer, and
[D 1 ] is an electron-withdrawing group. |
