发明名称 SYNTHESIS AND ISOLATION OF DENDRIMER BASED IMAGING SYSTEMS
摘要 The present invention relates to novel methods of synthesis and isolation of antibodies conjugated with modular dendrimer nanoparticles. In particular, the present invention is directed to antibodies conjugated with novel modular dendrimer nanoparticles having precise numbers of imaging agents, methods of synthesizing the same, compositions comprising such antibodies conjugated with such modular dendrimer nanoparticles, as well as systems and methods utilizing the conjugates (e.g., in imaging settings) (e.g., in diagnostic and/or therapeutic settings) (e.g., for the delivery of therapeutics, imaging, and/or targeting agents).
申请公布号 US2015352230(A1) 申请公布日期 2015.12.10
申请号 US201314760388 申请日期 2013.12.30
申请人 THE REGENTS OF THE UNIVERSITY OF MICHIGAN 发明人 Mullen Douglas Gurnett;Baker, JR. James R.;Banaszak Holl Mark M.;Huang Baohua;Dougherty Casey;Ball Jack
分类号 A61K49/00;C07K17/08 主分类号 A61K49/00
代理机构 代理人
主权项
地址 Ann Arbor MI US