| 摘要 |
According to the present invention, novel means for more reliably detecting sensitivity to Isoniazid (INH) in Mycobacterium tuberculosis, that is, detecting whether or not M. tuberculosis is an INH-resistant bacterium is provided. A method for detecting sensitivity to Isoniazid in M. tuberculosis, comprising the steps of obtaining a furA gene of M. tuberculosis in a sample and detecting a mutation involved in resistance to Isoniazid with respect to the obtained furA gene. The method of the invention may, if necessary, comprise a step of detecting a mutation in a fabG1 gene of M. tuberculosis, and may preferably be combined with another known method for detecting sensitivity to Isoniazid. |
