Microfluidic cartridge for separating target molecules, and separator and method of separating target molecules using same

摘要

A microfluidic cartridge includes a capture portion capturing target material on surfaces of nonmagnetic particles; and a separating portion separating target molecules from the target material captured on the surfaces of the particles. The microfluidic cartridge is mounted on an adaptor that is rotated by a rotating unit in order to separate a fluid including the target molecules from the particles through centrifugal force.

主权项

1. A microfluidic cartridge comprising:
a sample chamber, which contains a sample including a target material, the sample chamber including a first opening valve on an outlet of the sample chamber; a capture chamber, which contains nonmagnetic particles which capture the target material on surfaces of the nonmagnetic particles, connected to the sample chamber and including a filter on an outlet of the capture chamber, wherein the filter does not transmit the nonmagnetic particles; a waste chamber connected to the outlet of the capture chamber and including a first closing valve on an inlet of the waste chamber; a solution chamber, which contains a solution which separates target molecules from the target material captured on the surfaces of the nonmagnetic particles, including a third opening valve on an outlet of the solution chamber that is connected to the capture chamber; and a separation material receiving chamber including a fourth opening valve on an inlet that is connected to the capture chamber, and which receives a fluid including the target molecules from the capture chamber, wherein the microfluidic cartridge is mounted on an adaptor that is rotated by a rotating unit in order to separate the fluid including the target molecules from the nonmagnetic particles by the effect of centrifugal force.