发明名称 LIQUID COMPOSITION AND ITS PRODUCTION METHOD
摘要 PROBLEM TO BE SOLVED: To provide a liquid composition which has high transparency, enhances adsorption of vitamin A to a cornea, conjunctiva, nasal mucosa, and oral cavity and throat mucosa, and the like, and exhibits such effects more highly, and to provide a production method of the liquid composition which can keep a lower emulsification temperature, when compounding fat-soluble components such as vitamin A into the liquid composition.SOLUTION: The invention provides a liquid composition which can be obtained by adding an oil phase dissolving (A) vitamin A, (B) a nonionic surfactant, (C) antioxidative fat-soluble components excluding vitamin A, and (D) a polyhydric alcohol into an aqueous phase, stirring it at the emulsification temperature of 0-50°C to emulsify, wherein components (A)-(D) are contained, the formulation mass ratio represented by (D)/((A)+(C)) is 0.7-4, and the compounding amount of the component (B) is 0.05-0.15 W/V%.
申请公布号 JP2015224189(A) 申请公布日期 2015.12.14
申请号 JP20140108039 申请日期 2014.05.26
申请人 LION CORP 发明人 ORIHARA YOICHI
分类号 A61K31/203;A61K9/10;A61K47/10;A61K47/14;A61K47/34;A61P27/02 主分类号 A61K31/203
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