NOVEL EVALUATION METHOD FOR MELANOGENESIS INHIBITOR COMPRISING CO-CULTURE OF MELANOCYTE AND KERATINOCYTE

摘要

PROBLEM TO BE SOLVED: To provide an evaluation method for a material which inhibits melanogenesis of a melanocyte through a keratinocyte, and to provide a whitening material obtained from it.SOLUTION: A method for evaluating a melanogenesis inhibitory effect in a condition nearer to the practical skin by adding a whitening material in a co-culture of a melanocyte and keratinocyte is established. A whitening material expressing a melanogenesis inhibitory effect through the keratinocyte is also provided using the established co-culture method.