| 发明名称 |
TREATMENT OF ASTROCYTES-TUMOR CELLS INHIBITORS OF ENDOTHELIN RECEPTORS |
| 摘要 |
The disclosure relates to an endothelin receptor antagonist for use in the prevention or treatment of brain metastases in combination with a cytotoxic chemotherapy agent, radiotherapy or both. The endothelin receptor antagonist may for example be bosentan, macitentan or a mixture of bosentan and macitentan. |
| 申请公布号 |
US2015352113(A1) |
申请公布日期 |
2015.12.10 |
| 申请号 |
US201514640662 |
申请日期 |
2015.03.06 |
| 申请人 |
Board of Regents, The University of Texas System |
发明人 |
FIDLER Isaiah;KIM Sun-jin |
| 分类号 |
A61K31/513;A61N5/10;A61K31/337 |
主分类号 |
A61K31/513 |
| 代理机构 |
|
代理人 |
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| 主权项 |
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| 地址 |
Austin TX US |
