发明名称 IMIDAZO-PYRAZINE DERIVATIVES USEFUL AS SOLUBLE GUANYLATE CYCLASE ACTIVATORS
摘要 A compound of Formula II or a pharmaceutically acceptable salt thereof, are capable of modulating the body's production of cyclic guanosine monophosphate ("cGMP") and are generally suitable for the therapy and prophylaxis of diseases which are associated with a disturbed cGMP balance. The invention furthermore relates to processes for preparing compounds of Formula II, or a pharmaceutically acceptable salt thereof, for their use in the therapy and prophylaxis of the abovementioned diseases and for preparing pharmaceuticals for this purpose, and to pharmaceutical preparations which comprise compounds of Formula II or a pharmaceutically acceptable salt thereof.
申请公布号 WO2015187470(A1) 申请公布日期 2015.12.10
申请号 WO2015US33084 申请日期 2015.05.29
申请人 MERCK SHARP & DOHME CORP.;CAMPBELL, BRIAN, T.;DONG, GUIZHEN;GARFUNKLE, JOIE;KIM, ALEXANDER;ORNOSKI, OLGA;PARKER, DANN, L., JR.;RAGHAVAN, SUBHAREKHA;XU, LIBO;YANG, ZHIQIANG 发明人 CAMPBELL, BRIAN, T.;DONG, GUIZHEN;GARFUNKLE, JOIE;KIM, ALEXANDER;ORNOSKI, OLGA;PARKER, DANN, L., JR.;RAGHAVAN, SUBHAREKHA;XU, LIBO;YANG, ZHIQIANG
分类号 C07D487/04 主分类号 C07D487/04
代理机构 代理人
主权项
地址