发明名称 |
BIODEGRADABLE MICROBEADS WITH IMPROVED ANTICANCER DRUG ADSORPTIVITY, CONTAINING ALBUMIN AND DEXTRAN SULFATE, AND PREPARATION METHOD THEREFOR |
摘要 |
The present invention relates to: biodegradable microbeads with improved anticancer drug adsorptivity, containing albumin and dextran sulfate; a preparation method therefor; and a method for treating cancer using the same. The microbeads of the present invention is prepared from a biocompatible and biodegradable polymer so as to be safe to the human body, and can effectively inhibit the growth of a tumor by effectively blocking a blood vessel which supplies nutrition to a liver tumor and continuously releasing an anticancer drug adsorbed on surfaces of the beads. Therefore, the present invention can be useful for liver cancer chemoembolization. |
申请公布号 |
US2015352050(A1) |
申请公布日期 |
2015.12.10 |
申请号 |
US201314442901 |
申请日期 |
2013.11.15 |
申请人 |
UTAH-INHA DDS & ADVANCED THERAPEUTICS RESEARCH CENTER |
发明人 |
KIM Se Yoon;LEE Don Haeng;LI Yixian |
分类号 |
A61K9/16;A61K31/4745;A61K31/704 |
主分类号 |
A61K9/16 |
代理机构 |
|
代理人 |
|
主权项 |
1. Biodegradable microbeads with improved anticancer drug adsorptivity, the microbead comprising:
(i) albumin which is cross-linked to form a shape of a bead; and (ii) dextran sulfate, as an anionic polymer, included in the albumin cross-linked product. |
地址 |
Songdomirae-ro, Yeonsu-gu KR |