发明名称 FBXO3 INHIBITORS
摘要 A compound, or a pharmaceutically acceptable salt or ester thereof, having a structure of: wherein X is a divalent linking moiety; and R1-R10 are each individually H, optionally-substituted alkyl, optionally-substituted alkoxy, optionally-substituted aryl, optionally-substituted cycloalkyl, optionally-substituted heterocyclic, halogen, amino, or hydroxy, provided that at least one of R3 or R8 is an optionally-substituted alkyl, a substituted alkoxy, optionally-substituted aryl, optionally-substituted cycloalkyl, optionally-substituted heterocyclic, or halogen.
申请公布号 EP2858975(A4) 申请公布日期 2015.12.09
申请号 EP20130800256 申请日期 2013.03.13
申请人 UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION;THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS 发明人 CHEN, BEIBEI;MALLAMPALLI, RAMA, K.
分类号 C07D213/36;A61K31/137;A61K31/402;A61K31/5375;A61P3/10;A61P11/06;A61P19/00;A61P25/00;A61P35/00;C07C13/10;C07C15/12;C07D231/10;C07D233/60;C07D239/26;C07D277/28;C07D295/135;C07D307/52;C07D333/20;C07D413/12;C07D471/04;C07D471/10 主分类号 C07D213/36
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