发明名称 |
Combined inhibition of caspase-2 and caspase-6 in neuroprotection and axon regeneration |
摘要 |
The use of agents for the inhibition of caspase-2 and caspase-6 in the protection of central and peripheral neurons is disclosed. In particular, the invention comprises an inhibitor of caspase-2 for use in the treatment of a disease, a disorder or an injury of the nervous system by combined, sequential or separate administration with an inhibitor of caspase-6. Further provided is a composition comprising an inhibitor of caspase-2 and an inhibitor of caspase-6. The diseases may include ocular disorders or injuries, including ischemic optic neuropathy (ION) or other optical neuropathies. |
申请公布号 |
GB2526767(A) |
申请公布日期 |
2015.12.09 |
申请号 |
GB20140004289 |
申请日期 |
2014.03.11 |
申请人 |
THE UNIVERSITY OF BIRMINGHAM |
发明人 |
ZUBAIR AHMED;ANN LOGAN;MARTIN BERRY |
分类号 |
A61K38/48;A61K31/7088;A61P25/00;C12N15/113 |
主分类号 |
A61K38/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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