发明名称 糖尿病網膜症未発症の時期の糖尿病患者の網膜の外顆粒層の厚みに対する内網状層の相対的な厚みの変化、前記外顆粒層の厚みに対する内顆粒層の相対的な厚みの変化、及び神経節細胞層の厚みの変化の測定方法
摘要 Disclosed are a prevention/treatment agent for diabetic retinopathy characterized by containing lutein; said prevention/treatment agent, an ameliorating agent for an electroretinogram, an apoptosis suppression agent for retinal ganglion cells, a decrease suppression agent for molecules related to neural transmission, an ERK activation suppression agent, or a decrease suppression agent for brain-derived neurotrophic factors for being administered in the initial stage of diabetic retinopathy including simple retinopathy or preproliferative retinopathy; and a method for determining the dosing period of a prevention/ameliorating agent for diabetic retinopathy by means of comparing measured electroretinogram values with normal measured electroretinogram values, or by means of observing changes in the thicknesses of the inner plexiform layer, the inner granular layer, and the ganglion cell layer of the retina using optical coherence tomography.
申请公布号 JP5943338(B2) 申请公布日期 2016.07.05
申请号 JP20110529411 申请日期 2011.01.11
申请人 学校法人慶應義塾;株式会社わかさホールディングス 发明人 坪田 一男;小澤 洋子;佐々木 真理子;小林 沙織
分类号 A61B3/10 主分类号 A61B3/10
代理机构 代理人
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