| 主权项 |
1. A method, comprising:
detecting a first temperature related signal from a first temperature sensor, the first temperature related signal corresponding to a temperature of skin within a predetermined distance of a transcutaneously positioned analyte sensor, wherein the analyte sensor includes a plurality of electrodes comprising at least one working electrode, the working electrode including an analyte-responsive enzyme and a mediator, and at least one of the analyte-responsive enzyme and the mediator is chemically bonded to a polymer disposed on the working electrode, and further wherein at least one of the analyte-responsive enzyme and the mediator is crosslinked with the polymer; detecting a second temperature related signal from a second temperature sensor, the second temperature related signal corresponding to an ambient temperature in a housing of a data communication device, wherein the data communication device is operatively coupled to the analyte sensor and wherein the second temperature sensor is located at a predetermined distance from the first temperature sensor; estimating an analyte temperature related signal based on the first and second detected temperature related signals; and determining an analyte level in interstitial fluid based on the estimated analyte temperature related signal and a sensor signal from the transcutaneously positioned analyte sensor, wherein the first temperature related signal corresponding to the temperature of skin and the second temperature related signal corresponding to the ambient temperature in the housing are measured at a predetermined time of a sampling cycle of the analyte sensor;
wherein the analyte temperature related signal is estimated based on a predetermined value associated with the detected first and second temperature related signals; andwherein the predetermined value includes a ratio of thermal resistances associated with the first and second temperature sensors. |
