| 发明名称 | Treatment of cancers with immunostimulatory HIV Tat derivative polypeptides | ||
| 摘要 | Disclosed herein are methods of treating cancer by administering a modified Human Immunodeficiency Virus (HIV) trans-activator of transcription (Tat) polypeptide with increased immunostimulatory properties relative to the non-modified Tat polypeptide. | ||
| 申请公布号 | US9206239(B2) | 申请公布日期 | 2015.12.08 |
| 申请号 | US201313969917 | 申请日期 | 2013.08.19 |
| 申请人 | PIN PHARMA, INC. | 发明人 | Cohen David I. |
| 分类号 | C07K14/005;A61K31/675;A61K31/7088 | 主分类号 | C07K14/005 |
| 代理机构 | K&L Gates LLP | 代理人 | K&L Gates LLP ;Cullman Louis C.;Bergman Michelle Glasky |
| 主权项 | 1. A pharmaceutical composition comprising a modified amino acid sequence of Human Immunodeficiency Virus (HIV) trans-activator of transcription (Tat) protein wherein the modified amino acid sequence has greater than 95% sequence identity to the amino acid sequence of SEQ ID NO:2 or SEQ ID NO:3. | ||
| 地址 | New York NY US | ||