Medical devices and methods comprising an adhesive material

摘要

Improved medical devices and methods are provided that are implantable at or near a target tissue site beneath the skin of a patient, the medical device comprising an adhesive sheet having a region configured to receive a solid or semi-solid drug depot, the drug depot disposed within the region of the adhesive sheet, the drug depot having at least one surface configured to release a therapeutically effective amount of the drug over a period of at least one day, wherein the adhesive sheet limits movement of the medical device at or near the target tissue site. In some embodiments, the medical device provided can include an effective amount of at least one analgesic and/or at least one anti-inflammatory agent at or near a target site, and can reduce, prevent or treat inflammation and/or pain, such as postoperative pain or orthopedic degenerative pathology pain.

主权项

1. A medical device implantable at or near a target tissue site beneath the skin of a patient, the medical device configured for implantation beneath the skin and comprising an adhesive sheet and a biodegradable solid or semi-solid drug depot, the drug depot having at least one surface configured to release a therapeutically effective amount of a drug over a period of at least one day, the adhesive sheet comprising a plurality of regions, each of the regions comprising at least two slits substantially parallel to each other and disposed in or on the adhesive sheet, the drug depot being substantially perpendicular to each of the slits, the drug depot being slidably received by each of the slits in one of the regions to hold the drug depot.