| 发明名称 |
MACROCYCLIC INHIBITORS OF THE PD-1/PD-L1 AND CD80(B7-1)/PD-L1 PROTEIN/PROTEIN INTERACTIONS. |
| 摘要 |
The present disclosure provides novel macrocyclic peptides which inhibit the PD-1/PD-L1 and PD-L1/CD80 protein/protein interaction, and thus are useful for the amelioration of various diseases, including cancer and infectious diseases. |
| 申请公布号 |
MX2015011731(A) |
申请公布日期 |
2015.12.07 |
| 申请号 |
MX20150011731 |
申请日期 |
2014.03.13 |
| 申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
LI-QIANG SUN;ERIC MULL;ERIC P. GILLIS;MICHAEL S. BOWSHER;PAUL MICHAEL SCOLA;CLAUDIO MAPELLI;DAVID R. LANGLEY;MICHAEL MATTHEW MILLER;MARTIN PATRICK ALLEN;KENNETH M. BOY;MAUDE A. POIRIER;NISHITH SANGHVI;DANIEL J. TENNEY;KAP-SUN YEUNG;JULIAN ZHU;PATRICK C. REID |
| 分类号 |
C07K7/56;A61K38/12;C07K7/08;G01N33/68 |
主分类号 |
C07K7/56 |
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