发明名称 |
Method For Production Of Large Numbers Of Cartilage Cells With Phenotype Retention |
摘要 |
A method for production of large numbers of cartilage cells with phenotype retention intended for treatment of articular cartilage lesions or preparing viable cartilage tissue by propagation of chondrocytes from cartilage explants, human or animal, with the retention of phenotypes of the cartilage cells, in which cells are chondrocytes retaining morphologic attributes of the same or chondrocyte progenitor cells. The method includes culturing the cells in which cultured cells are organized into mature hyaline cartilage on the surface of biologic structures such as cancellous or cortical bone lamina. The method for culturing chondrocytes to produce three dimensional cellular structures consisting of cartilage cells and cell produced extracellular cartilage matrix. |
申请公布号 |
US2015344847(A1) |
申请公布日期 |
2015.12.03 |
申请号 |
US201414290438 |
申请日期 |
2014.05.29 |
申请人 |
Malinin Theodore I |
发明人 |
Malinin Theodore I |
分类号 |
C12N5/077 |
主分类号 |
C12N5/077 |
代理机构 |
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代理人 |
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主权项 |
1. A method for production of large numbers of cartilage cells comprises the step of:
preparing viable cartilage tissue by propagation of chondrocytes from cartilage explants, human or animal, with the retention of phenotypes of the cartilage cells. |
地址 |
Key Biscayne FL US |