IRCINIASTATIN ANALOGUES

摘要

The present invention is directed to irciniastatin analogues. Uses of these analogues also described.

主权项

1. A compound of Formula I, or a stereoisomer thereof, wherein R1 is hydrogen; and R2 is halogen, O—C(O)phenyl, O—C(O)C1-6alkyl, OC1-6alkyl; or C1-6 alkyl, or wherein R1 and R2 together form ═CR3R4 or ═NR5 wherein R3 and R4 are independently hydrogen or C1-6 alkyl, and R5 is O—C1-6 alkyl; or a pharmaceutically acceptable salt thereof.