发明名称 |
NEUROTROPHIN-TYROSINE KINASE RECEPTOR SIGNALING |
摘要 |
The invention relates to a method of regulating neurotrophin-tyrosine kinase receptor signaling in a cell comprising modulating the interaction between the juxtamembrane region of the intracellular domain of the neurotrophin receptor p75 and Trk. The invention also relates to compositions comprising compounds which modulate the interaction between the juxtamembrane region of the intracellular domain of the neurotrophin receptor p75 and Trk, and use of the compounds and compositions for the treatment of neurotrophin-Trk signaling related diseases and disorders. |
申请公布号 |
US2015344535(A1) |
申请公布日期 |
2015.12.03 |
申请号 |
US201314432190 |
申请日期 |
2013.09.27 |
申请人 |
THE UNIVERSITY OF QUEENSLAND |
发明人 |
COULSON Elizabeth Jane;MATUSICA Dusan;BREDY Timothy William;SKELDAL Sune |
分类号 |
C07K14/47;G01N33/566 |
主分类号 |
C07K14/47 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
Queensland AU |