发明名称 |
Process for the production of ultrapure galacto-oligosaccharides |
摘要 |
The present invention describes a process for preparing ultrapure (≧95%) galacto-oligosaccharides (GOS), starting from GOS at lower purities by using sequential microbiological purifications involving Saccharomyces cerevisiae and Streptococcus thermophilics. |
申请公布号 |
US9200303(B2) |
申请公布日期 |
2015.12.01 |
申请号 |
US201013388721 |
申请日期 |
2010.08.06 |
申请人 |
Ritter Pharmaceuticals, Inc. |
发明人 |
Giacomelli Silvia;Manoni Marco;Cipolletti Giovanni;Biagiolini Silvia;Vagnoli Luana;Chini Jacopo |
分类号 |
C12N1/00;C12P19/04 |
主分类号 |
C12N1/00 |
代理机构 |
Knobbe Martens Olson & Bear LLP |
代理人 |
Knobbe Martens Olson & Bear LLP |
主权项 |
1. A process for purifying a GOS mixtures and obtaining it with a purity ≧95% in which the overall percentage of the digestible sugars lactose, glucose and galactose is ≦5%, said process comprising subjecting a starting GOS mixture with a purity ≦95% in which the overall percentage of the digestible sugars lactose, glucose and galactose is ≧5%, to a fermentation step with Streptococcus thermophilus and at least one fermentation step with Saccharomyces cerevisiae, wherein said fermentation step with S. thermophilus hydrolyses lactose then consumes the glucose produced and accumulates galactose which is then eliminated by S. cerevisiae where said purity is calculated by any analytical method able to distinguish and quantify GOS and said digestible sugars. |
地址 |
DE US |