Process for the preparation of chiral hydrazides

摘要

The present invention relates to a process for the preparation of a chiral compound according to formula (V) wherein R1 is preferably an alkyl residue preferably having from 1 to 6 carbon atoms, in particular to a process for the preparation of a chiral compound the crystalline chiral compounds as such, and their use for the preparation of an antifungal agent, in particular posaconazole.;

主权项

1. An optionally crystalline chiral compound of formula (II) wherein Y is an optionally substituted aryl moiety, wherein at least 95% of the molecules of said optionally crystalline compound are present as isomer of formula (IIa)