| 发明名称 |
MAC-1 ANTIBODIES AND USES THEREOF |
| 摘要 |
A method of treating a subject having or at risk of a disease or disorder associated with aberrant leukocyte-platelet interactions includes administering to the subject a therapeutically effective amount of a monoclonal antibody or antigen binding portion thereof that specifically binds to at least one of SEQ ID NO: 1, SEQ ID NO: 2, or SEQ ID NO: 3 to inhibit leukocyte arrest on adherent platelets in the subject. |
| 申请公布号 |
US2015337039(A1) |
申请公布日期 |
2015.11.26 |
| 申请号 |
US201514719984 |
申请日期 |
2015.05.22 |
| 申请人 |
Case Western Reserve University |
发明人 |
Simon Daniel I. |
| 分类号 |
C07K16/28 |
主分类号 |
C07K16/28 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of treating a subject having or at risk of a disease or disorder associated with aberrant leukocyte-platelet interactions, the method comprising:
administering to the subject a therapeutically effective amount of a monoclonal antibody or antigen binding portion thereof that specifically binds to at least one of SEQ ID NO: 1, SEQ ID NO: 2, or SEQ ID NO: 3 to inhibit leukocyte arrest on adherent platelets in the subject. |
| 地址 |
Cleveland OH US |
