ENANTIOPURE HAPTENS FOR NICOTINE VACCINE DEVELOPMENT

摘要

The invention provides chiral haptens (-)-3'-AmNic and (-)-N4N for use in generating antibodies in a patient specific for (-)-nicotine. The haptens can be conjugated to suitable carrier proteins and administered as an antigenic mixture, optionally comprising adjuvant(s), to a patient suffering from nicotine or tobacco addiction or habituation.