A COMBINATION OF AN AKT INHIBITOR AND AT LEAST ONE OF CYCLOOXYGENASE-2 INHIBITOR AND A 5-LIPOXYGENASE INHIBITOR FOR TREATING CANCER

摘要

The present disclosure relates to a pharmaceutical composition and a kit to treat cancer. The disclosure provides a composition comprising AKT inhibitor and at least one of cyclooxygenase-2 inhibitor and 5-lipoxygenase inhibitor. The disclosure further relates to a process of preparing the said composition and a method of treating cancer comprising PTEN mutation/AKT mutation/ PI3K mutation alone or in combination with each other or in combination with mutations in other genes causing cancer.