| 发明名称 |
METHODS OF TREATING PR-POSITIVE, LUMINAL A BREAST CANCER WITH PI3K INHIBITOR, PICTILISIB |
| 摘要 |
Methods and compositions are provided for treating breast cancer in patients with a PI3K inhibitor, GDC-0941 in combination with an endocrine therapy agent.; |
| 申请公布号 |
US2015335650(A1) |
申请公布日期 |
2015.11.26 |
| 申请号 |
US201514717069 |
申请日期 |
2015.05.20 |
| 申请人 |
Genentech, Inc. |
发明人 |
Derynck Mika K.;Friedman Lori;Gendreau Steven Brian;Milan Sandra |
| 分类号 |
A61K31/5377;A61K31/4196;G01N33/50;C12Q1/68;G01N33/574;A61K45/06;A61K31/565 |
主分类号 |
A61K31/5377 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of treatment comprising administering a therapeutically effective amount of GDC-0941 and an endocrine therapy agent to a patient with PR+ or luminal A-type breast cancer, wherein GDC-0941 has the structure: including stereoisomers, geometric isomers, tautomers, and pharmaceutically acceptable salts thereof. |
| 地址 |
South San Francisco CA US |
