主权项 |
1. A method for inhibiting the degradation of collagen in skin, the method comprising: topically administering to the skin an effective amount of a composition comprising:
(a) an antioxidant compound of formula I: wherein R is C1-C10 alkyl, C3-C12 cycloalkyl, aryl, or aryl-alkyl; R1, R2, R3, R4, and R5 are independently H, C1-C10 alkyl, hydroxy, C1-C6 alkoxy, —COOH, —COO−M+, or —O−M+, where M+ is sodium or potassium or ammonium ion, provided that at least one of R1, R2, R3, R4, and R5 is hydroxy; and R6 is H, C1-C10 alkyl, C3-C12 cycloalkyl or phenyl; and (b) a dermatologically acceptable carrier. |