发明名称 |
BIPHENYLOXYBENZENSULPHONAMIDE DERIVATIVES USEFUL AS SODIUM CHANNEL INHIBITORS |
摘要 |
<p>The invention relates to sulfonamide derivatives, to their use i n medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to new sulfonamide Nav1.7 inhibitors of formula (I): or pharmaceutically acceptable salts thereof, wherein Z1, Ra, Rb, R1, R2, R3, R4 and R5 are as defined in the description. Nav 1.7 inhibitors are potentially useful in the treatment of a wide range of disorders, particularly pain.</p> |
申请公布号 |
CA2804593(C) |
申请公布日期 |
2015.11.24 |
申请号 |
CA20112804593 |
申请日期 |
2011.07.05 |
申请人 |
PFIZER LIMITED;ICAGEN, INC. |
发明人 |
BROWN, ALAN DANIEL;DE GROOT, MARCEL JOHN;MARRON, BRIAN EDWARD;RAWSON, DAVID JAMES;RYCKMANS, THOMAS;STORER, ROBERT IAN;STUPPLE, PAUL ANTHONY;SWAIN, NIGEL ALAN;WEST, CHRISTOPHER WILLIAM |
分类号 |
C07D417/12;A61K31/501;A61P29/00;C07D237/20;C07D285/135;C07D401/12;C07D403/12;C07D417/14 |
主分类号 |
C07D417/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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