Pharmaceutical formulations and uses thereof in the treatment of female sexual dysfunction

摘要

The present invention relates to the use of a combination of a PDE5-inhibitor and testosterone for the preparation of a medicament for the treatment of Female Sexual Dysfunction.

主权项

1. A pharmaceutical formulation comprising:
testosterone or an analog thereof and a PDE5 inhibitor wherein said analog of testosterone is a precursor or a metabolite of testosterone having the same kind of activity as testosterone; wherein said formulation is designed to release the testosterone or analog thereof within a time interval of 60 seconds upon administration; wherein said PDE5-inhibitor is released after said testosterone or analog is released such that the effects of the PDE5-inhibitor and testosterone or analog coincide; and wherein said PDE5-inhibitor is released 1.5-4.5 hours after the testosterone or analog is released.