摘要 |
FIELD: pharmacology.SUBSTANCE: as compound, possessing antispasmodic activity claimed is dihydrochloride 9-dialkylaminoethyl-2-(4-chlorophenyl)imidazol[1,2-a]benzimidazole of general formula Iwhere Ia NR= dimethylamino- Ib NR= diethylamino-. Therapeutic index of dihydrochloride 9-dialkylaminoethyl-2-(4-chlorophenyl)imidazol[1,2-a]benzimidazole was in 10 times higher than of sodium valproate.EFFECT: antispasmodic activity of compounds exceeding activity of sodium valproate has been identified.2 cl, 3 tbl |