| 发明名称 |
ANTI-CXCR1 COMPOSITIONS AND METHODS CXCR1 |
| 摘要 |
<p>The present invention provides methods of treating cancer by administering an IL8-CXCR1 pathway inhibitor (e.g., an anti-CXCR1 antibody or Repertaxin) alone or in combination with an additional chemotherapeutic agent such that non-tumorigenic and tumorigenic cancer cells in a subject are killed. The present invention also provides compositions and methods for detecting the presence of and isolating solid tumor stem cells in a patient (e.g., based on the presence of CXCR1 or FBXO21).</p> |
| 申请公布号 |
HK1161350(A1) |
申请公布日期 |
2015.11.20 |
| 申请号 |
HK20120101909 |
申请日期 |
2012.02.24 |
| 申请人 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN |
发明人 |
WICHA, MAX S.;GINESTIER, CHRISTOPHE |
| 分类号 |
G01N |
主分类号 |
G01N |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
