| 摘要 |
PROBLEM TO BE SOLVED: To provide novel therapeutic methods of amyotrophic lateral sclerosis (ALS), Alzheimer's disease (AD), or multiple sclerosis (MS).SOLUTION: The present invention relates to therapeutic methods of treating a macrophage-associated neurodegenerative disease, such as amyotrophic lateral sclerosis (ALS), Alzheimer's disease (AD), or multiple sclerosis (MS) in a subject by administering chlorite in an amount effective to decrease blood immune cell activation. Chlorite is administered in the form of the matrix of chlorite ions, such as tetrachlorodecaoxygen, or in the form of a pharmaceutically acceptable chlorite salt, such as sodium chlorite. The invention also relates to the therapeutic methods of monitoring therapy by assessing blood immune cell activation before and after therapy. |
