| 摘要 |
PROBLEM TO BE SOLVED: To provide methods, monoclonal antibodies, polyclonal antibodies, assays, and kits for detecting HPV infection and HPV related cancer diagnosis, including infection by various HPV genotypes, early and/or late stage HPV-associated or HPV-specific cancers.SOLUTION: The invention relates to various monoclonal antibodies recognizing specific epitope for specific HPV protein or HPV type, and common epitope for various HPV proteins or HPV types. The monoclonal antibodies are useful means in early clinical detection of HPV infection and general detection of HPV related diseases, specific detection of invasive cervical cancer, detection of other HPV related cancers in early stage precancerous lesions as well as late stage cancer progression. |
