发明名称 |
Biomaterial compositions |
摘要 |
Biomaterial compositions comprising organosilicon monomers (such as silorane monomers) and chemical curing systems or dual chemical/light curing systems, in conjunction with optional tetraoxaspiro[5.5]undecanes (“TOSUs”) and/or fillers. The present invention is directed to biomaterial compositions, as well as methods for manufacturing the same, and methods of using the compositions. The biomaterial composition comprises one or more organosilicon monomers (such as a silorane) and a chemical curing system or dual chemicaVlight curing system for polymerizing the 10 monomer(s). The compositions may include one or more tetraoxaspiro[5.5]undecanes “TOSUs”) and/or fillers. Accelerators (such as photoacids), photosensitizers, and/or electron donors may also be included in the composition as appropriate. |
申请公布号 |
US9186302(B2) |
申请公布日期 |
2015.11.17 |
申请号 |
US201113880783 |
申请日期 |
2011.10.28 |
申请人 |
CURATORS OF THE UNIVERSITY OF MISSOURI |
发明人 |
Kilway Kathleen V.;Bonewald Lynda F.;Schuman Thomas P. |
分类号 |
A61K6/093;A61K6/00;A61L24/04;A61L27/18;C08F2/50;C08G77/60 |
主分类号 |
A61K6/093 |
代理机构 |
Stinson Leonard Street LLP |
代理人 |
Stinson Leonard Street LLP |
主权项 |
1. A biomaterial composition comprising:
a polymerizable silorane monomer, and a curing system selected from the group consisting of a chemical curing system and a dual chemical/light curing system, wherein the curing system comprises a rhodium-based or platinum-based organometallic catalyst, and wherein said silorane monomer comprises a mixture of 2,4,6,8-tetramethyl-2,4,6,8-tetrakis-[2-(7-oxabicyclo[4.1.0]hept-3-yl)ethyl]-1,3,5,7-tetraoxa-2,4,6,8-tetrasilacyclooxtane (CYGEP) and methylbis[2-(7-oxabicyclo[4.1.0]hept-3-yl)ethyl]phenylsilane (PHEPSI). |
地址 |
Columbia MO US |