发明名称 Methods of treating vascular lesions
摘要 Described are methods of treating virus-associated lesions using administration of an anti-angiogenic compound, or a combination of angiolytic or ablative therapy and administration of an anti-angiogenic compound.
申请公布号 US9186336(B2) 申请公布日期 2015.11.17
申请号 US201013147844 申请日期 2010.02.05
申请人 The General Hospital Corporation 发明人 Zeitels Steven M.
分类号 A61K31/00;C07K16/22 主分类号 A61K31/00
代理机构 Fish & Richardson P.C. 代理人 Fish & Richardson P.C.
主权项 1. A method of treating laryngeal recurrent respiratory papillomatosis (RRP) and maintaining or improving mucosal pliability in the larynx in a human subject, the method comprising locally administering to a phonatory mucosal surface in the larynx of the subject in need thereof an anti-VEGF antibody that binds to human VEGF-A in an amount effective to inhibit RRP and to maintain or improve mucosal pliability in the larynx.
地址 Boston MA US