发明名称 HELICASE-PRIMASE INHIBITORS FOR USE IN A METHOD OF TREATING ALZHEIMER'S DISEASE.
摘要 The present invention relates to the use of helicase-primase inhibitors in a method of treating Alzheimer's Disease (AD). Particularly, the present invention relates to the use of helicase-primase inhibitors in a method of treating AD in a subject that is having HSV-1 infection and is having AD or is having HSV-1 infection and is suspected of having AD. The provided antiviral helicase-primase inhibitors affect the accumulation of the key AD proteins amyloid beta and abnormally phosphorylated tau that occur during HSV-1 infection.
申请公布号 MX2015010339(A) 申请公布日期 2015.11.16
申请号 MX20150010339 申请日期 2014.02.12
申请人 AICURIS GMBH & CO. KG 发明人 RUTH ITZHAKI
分类号 A61K31/426;A61K31/427;A61P25/28 主分类号 A61K31/426
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