发明名称 |
CS1-specific chimeric antigen receptor engineered immune effector cells |
摘要 |
Disclosed herein are chimeric antigen receptors (CAR) that can specifically recognize tumor- associated antigens (TAA) on multiple myeloma (MM) cells. Also disclosed are immune effector cells, such as T cells or Natural Killer (NK) cells, that are engineered to express these CARs. Therefore, also disclosed are methods of providing an anti-tumor immunity in a subject with MM that involves adoptive transfer of the disclosed immune effector cells engineered to express the disclosed CARs. |
申请公布号 |
AU2014259675(A1) |
申请公布日期 |
2015.11.12 |
申请号 |
AU20140259675 |
申请日期 |
2014.05.02 |
申请人 |
OHIO STATE INNOVATION FOUNDATION |
发明人 |
YU, JIANHUA;HOFMEISTER, CRAIG;CHU, JIANHONG |
分类号 |
C07K19/00 |
主分类号 |
C07K19/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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