| 发明名称 |
Crystalline and non- crystalline forms of tofacitinib, and a pharmaceutical composition comprising tofacitinib and a penetration enhancer |
| 摘要 |
<p>The present invention discloses novel crystalline and non-crystalline forms of 3-((3R, 4R)-4-methyl-3-[methyl-(7H-pyrrolo[2, 3-d]pyrimidin-4-yl)-amino]-piperidin-1-yl)-3-oxopropionitrile, pharmaceutical composition containing the same, preparations thereof and the uses thereof.</p> |
| 申请公布号 |
AU2012241018(B2) |
申请公布日期 |
2015.11.12 |
| 申请号 |
AU20120241018 |
申请日期 |
2012.03.29 |
| 申请人 |
PFIZER INC. |
发明人 |
MURPHY, BRENDAN J.;WHITE, TIMOTHY D.;CHEKAL, BRIAN P.;JOHNSON, PHILLIP J.;FOTI, CHRISTOPHER JAMES;MARGULIS, LEONID A. |
| 分类号 |
C07D487/04;A61K31/519;A61P17/06 |
主分类号 |
C07D487/04 |
| 代理机构 |
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代理人 |
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