发明名称 Crystalline antifungal compounds
摘要 Novel crystalline forms of (1R,2R)-7-chloro-3-[2-(2,4-difluorophenyl)-2 -hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]quinazolin-4(3H)-one, pharmaceutical compositions containing these crystalline forms, methods of using these crystalline forms for treating and/or preventing various microbial and/or fungal infections or disorders, and processes for obtaining these crystalline forms. In particular, the present subject matter relates to the specific crystalline Forms I, II, III, IV, V, and VI of (1R,2R)-7-chloro-3-[2 -(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]quinazolin -4(3H)-one, represented by formula II:
申请公布号 US7879867(B2) 申请公布日期 2011.02.01
申请号 US20070882892 申请日期 2007.08.06
申请人 PALAU PHARMA, S.A.;STIEFEL LABORATORIES, INC. 发明人 PAREDES ANTONIO CANOVAS;ORPI JAVIER BARTROLI;GRAU ELIES MOLINS;SERRA ANNA ROIG;MEYER KEVIN;LORIMER KEITH
分类号 A61K31/517 主分类号 A61K31/517
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