Apparatus for treatment of reperfusion injury

摘要

An apparatus to minimize and/or eliminate the effects associated with reperfusion injury consisting of an external pump, heat exchanger and control unit creating a flow loop whereby blood is moved from the body via a pump, cooled by an external heat exchanger and reintroduced into a specific location, thereby locally cooling the surrounding tissue and inducing localized hypothermia to minimize tissue injury resulting from ischemia and the effects associated with reperfusion injury as an obstruction is removed and normal blood flow is restored and including the ability to locally measure pressure and temperature in the body.

主权项

1. A fluid cooling apparatus for the treatment of reperfusion injury and ischemia, comprising:
a control module having a control panel and a control unit; a pump operatively coupled to the control module; a heat exchanger operatively coupled to the control module; a fluid flow loop linking the pump and heat exchanger, said fluid flow loop including a catheter configured to deliver a flow of fluid to a specific location within a patient's body; a pressure probe monitoring localized pressure within the fluid flow loop, said pressure probe operatively coupled to the control unit; wherein the pump is configured to move fluid through the flow loop from one location within a patient's body or an external reservoir; wherein the heat exchanger is configured to cool the fluid within the flow loop; and wherein the control unit is configured with a feedback control to monitor and adjust the pump pressure, the amount of cooling delivered by the heat exchanger, and a localized pressure within the patient's body to overcome ventricularization, resonance, and dampening within the vasculature of the body.