Method for determining at least one diagnosis or risk assessment parameter related to AMD

摘要

A method for Determining at Least One Parameter for Diagnosis or Risk Assessment of a Disease, including AMD. The distribution of the macular pigment MP of an eye and at least one area A whose bordering line corresponds to a constant optical density MPD and/or concentration MPC of MP is determined by an analysis unit. The bordering line is subjected to a quantitative shape description. At least one parameter DP, suitable for diagnosing a disease and/or the risk of a disease is derived from the quantitative shape description of the bordering line of the areas A. The method is provided for diagnosis or risk assessment but may also be used in the context of treatment of macular pigment deficiency phenomena to select the required supplements. This method, based on the determination of the fractal dimension, is also suitable for diagnosing other diseases such as edemas, actinomycoses, atrophies or lesions.

主权项

1. A method for determining at least one parameter for diagnosing or assessing the risk of a disease, including the risk of developing the disease of Aging related Macular Degeneration (AMD), the method comprising:
determining a distribution of the macular pigment MP of an eye; determining at least one area whose bordering line corresponds to a constant optical density MPD and/or concentration MPC of the macular pigment by an analysis unit from the distribution of the macular pigment MP; and subjecting the at least one area to a quantitative shape description by determining a fractal dimension FD of the bordering line as a standardized value FDnorm, wherein the fractal dimensions FD or FDnorm are indicative of a disease-related change when a predetermined limit value is exceeded; and deriving at least one parameter DP which is suitable for diagnosing a disease and/or the risk of developing the disease of AMD and/or monitoring its treatment from the quantitative shape description of the bordering line of the area.