发明名称 Imaging diagnostics by combining contrast agents
摘要 The present invention relates to the use of a combination of several contrast agents having different properties with respect to imaging representation.
申请公布号 US9179882(B2) 申请公布日期 2015.11.10
申请号 US201313860675 申请日期 2013.04.11
申请人 MIVENION GMBH 发明人 Wiebelitz Ulrike
分类号 A61K51/04;A61K49/00;A61B6/00;A61K49/04;A61K49/06;A61K49/10;A61B6/03 主分类号 A61K51/04
代理机构 Millen, White, Zelano & Branigan P.C. 代理人 Millen, White, Zelano & Branigan P.C.
主权项 1. A polymodal method for imaging a lesion in a patient comprising: administering to said patient: an extracellular contrast medium (ECCM) comprising gadolinium-DTPA, anda lesion-specific contrast medium (LSCM) different from the ECCM, which is enriched in the lesion 10 minutes after administration to said patient and is retained in the lesion for at least 1 hour, wherein the LSCM is 18F-fluorodesoxyglucose (FDG), 18F-dopamine, 18F-L-DOPA, 18F-fluorocholine, 18F-fluoromethylethylcholine, or 18F-fluorodihydrotestosterone subjecting the patient to polymodal imaging wherein at least two different imaging modalities are used to provide at least two different imaging signals which are immediately interpolated by a fusion method of the at least two different imaging modalities and wherein the ECCM and LSCM are applied at the same time or the LSCM is applied with a short time delay of 30 minutes maximum after the ECCM.
地址 Berlin DE
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