发明名称 |
Imaging diagnostics by combining contrast agents |
摘要 |
The present invention relates to the use of a combination of several contrast agents having different properties with respect to imaging representation. |
申请公布号 |
US9179882(B2) |
申请公布日期 |
2015.11.10 |
申请号 |
US201313860675 |
申请日期 |
2013.04.11 |
申请人 |
MIVENION GMBH |
发明人 |
Wiebelitz Ulrike |
分类号 |
A61K51/04;A61K49/00;A61B6/00;A61K49/04;A61K49/06;A61K49/10;A61B6/03 |
主分类号 |
A61K51/04 |
代理机构 |
Millen, White, Zelano & Branigan P.C. |
代理人 |
Millen, White, Zelano & Branigan P.C. |
主权项 |
1. A polymodal method for imaging a lesion in a patient comprising:
administering to said patient:
an extracellular contrast medium (ECCM) comprising gadolinium-DTPA, anda lesion-specific contrast medium (LSCM) different from the ECCM, which is enriched in the lesion 10 minutes after administration to said patient and is retained in the lesion for at least 1 hour, wherein the LSCM is 18F-fluorodesoxyglucose (FDG), 18F-dopamine, 18F-L-DOPA, 18F-fluorocholine, 18F-fluoromethylethylcholine, or 18F-fluorodihydrotestosterone subjecting the patient to polymodal imaging wherein at least two different imaging modalities are used to provide at least two different imaging signals which are immediately interpolated by a fusion method of the at least two different imaging modalities and wherein the ECCM and LSCM are applied at the same time or the LSCM is applied with a short time delay of 30 minutes maximum after the ECCM. |
地址 |
Berlin DE |