主权项 |
1. An isolated polypeptide comprising the polypeptide sequence according to general formula I
R1-R2-Phe-R3-R4-R5-R6-R7-R8-R9-R10-R11-R12-R13-R14-R15-R16-R17 (SEQ ID NO: 1), wherein R1 is selected from the group consisting of Ser, Ala, Phe, His, Lys, Met, Asn, Gln, Thr, Val, Tyr, and Asp; R2 can be any amino acid; R3 is selected from the group consisting of Asp, Ala, Glu, Gly, Asn, Pro, Ser, and Tyr; R4 is selected from the group consisting of Leu and Phe; R5 can be any amino acid; R6 is selected from the group consisting of Met, Phe, His, Ile, Leu, Gln, and Thr; R7 is selected from the group consisting of Arg, Gly, Lys, Gln, and Thr; R8 is selected from the group consisting of Ile, Asn, Gln, Val, and Trp; R9 is selected from the group consisting of Met, Gly, Ile, Lys, Leu, Asn, Arg, Ser, Thr, Val, His, and Tyr; R10 is selected from the group consisting of Trp and Phe; R11 is selected from the group consisting of Ile, Phe, Ser, Thr, and Val; R12 is selected from the group consisting of Tyr, Cys, Asp, Phe, His, Asn, and Ser; R13 is selected from the group consisting of Val, Ala, Phe, Ile, Leu, Asn, Gln, Thr, and Tyr; R14 is selected from the group consisting of Phe, Glu, and Leu; R15 is selected from the group consisting of Ala, Gly, Lys, Arg, and Ser; and R16 is selected from the group consisting of Phe, Cys, His, Lys, Leu, Met, Asn, Gln, Arg, Thr, Val, Trp, and Tyr; wherein at least one of the following is true: R3 is Asp, R6 is Met, R10 is Trp, or R14 is Phe. |