摘要 |
<p>Abstract The invention relates to compounds of Formula A: R2 'R6 R8 Rg R5 Re HO' -1 4 or a salt, solvate, hydrate, or prodrug thereof The compounds of Formula A are TGR5 modulators useful for the treatment of various 5 diseases, including metabolic disease, inflammatory disease, liver disease, autoimmune disease, cardiac disease, kidney disease, cancer, and gastrointestinal disease.</p> |