PRODUCTION OF HETEROLOGOUS POLYSACCHARIDES IN PLANTS

摘要

The invention relates to a novel method for producing bacterial or viral saccharides, such as capsular, immunogenic or membrane saccharides, in a plant cell. Also provided plants, plant cells, plant parts, and plant products comprising such a bacterial or viral saccharide. The invention is based upon the novel finding that bacterial enzymes can be used in a plant cell to produce bacterial or viral capsular, immunogenic and/or membrane saccharides.

主权项

1. A method of producing a bacterial capsular saccharide, a bacterial membrane saccharide and/or a bacterial or viral immunogenic saccharide in a host plant cell, the method comprising:
1) providing a plant cell; 2) introducing into the plant cell a heterologous protein or nucleotide sequence which enables the production of the bacterial or viral saccharide in the plant cell; 3) maintaining the host plant cell under suitable conditions for saccharide biosynthesis; and optionally 4) harvesting the bacterial or viral saccharide from the host plant cell.