发明名称 MINIMALLY TOXIC PRODRUGS
摘要 The present invention relates to the field of oligopeptide prodrugs that are intended for the treatment of cancer. The selectivity of these prodrugs requires the presence of an (oligo)peptidic moiety and/or a protective capping group to ensure the prodrug stability in blood. It further in particular relates to the exemplary oligopeptidic moiety ALGP and to prodrugs comprising it. In particular it also relates to the capping group phosphonoacetyl and to prodrugs comprising this capping group.
申请公布号 EP2938360(A2) 申请公布日期 2015.11.04
申请号 EP20130820778 申请日期 2013.12.27
申请人 LIFE SCIENCES RESEARCH PARTNERS VZW 发明人 TROUET, ANDRÉ
分类号 A61K45/06;A61K47/48;C12Q1/37 主分类号 A61K45/06
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