Method for calculating tear film lipid and aqueous layer thicknesses and corneal surface refractive index from interferometry data

摘要

Disclosed herein is a method of calculating tear film lipid and aqueous layer thicknesses and/or corneal surface refractive index from interferometry data obtained from simultaneous measurements of the aqueous and lipid layers of the tear film along with a measurement of the corneal surface reflectance.

主权项

1. A method of evaluating an ocular environment of a patient comprising:
(a) selecting the patient; (b) aligning an eye of the patient with light originating from a light source; (c) measuring light reflectance from the eye; (d) fitting the light reflectance to a mathematical construct based upon a characteristic mathematical matrix of a thin film stack comprising in sequence from top to bottom: air as a boundary, a tear film lipid layer, a tear film aqueous layer and a contact lens as a semi-infinite substrate; and (e) determining a parameter selected from the group consisting of lipid layer thickness, aqueous layer thickness and contact lens surface refractive index.