发明名称 X-ray imaging contrast media with low iodine concentration and x-ray imaging process
摘要 Disclosed an X-ray composition comprising ioforminol and a pharmaceutically acceptable carrier or excipient, wherein the composition comprises an iodine concentration of 10-200 mg I/ml and a sodium ion concentration of 70-120 Mm and preferably a calcium ion concentration of 0.5-1.3 mM. Also disclosed is the use of ioforminol in the manufacture of a diagnostic composition for use in a diagnostic method, wherein the method comprises examining a body to which the diagnostic composition and an X-ray radiation dose has been administered, with a diagnostic device and compiling data from the examination; and the composition comprises an iodine concentration of 10-200 mg I/ml and a sodium ion concentration of 70-120 mM. Further disclosed is the use of ioforminol in the manufacture of a diagnostic composition for use in an in vivo imaging detection method, wherein the in vivo imaging detection method comprises administering the composition to a body, applying an X-ray radiation dose to the body, examining the body with a diagnostic device and compiling data from the examination; and the composition comprises an iodine concentration of 10-200 mg I/ml and a sodium ion concentration of 70-120 mM.
申请公布号 NZ626988(A) 申请公布日期 2015.10.30
申请号 NZ20130626988 申请日期 2013.01.10
申请人 GE HEALTHCARE AS 发明人 NEWTON BEN;THANING MIKKEL;VELD DIRK-JAN IN&rsquo,T;LANGSETH KARINA;EVANS PAUL MICHAEL
分类号 A61K49/04;A61K31/047;A61K31/164;A61K31/166;C07C233/69;C07C233/88 主分类号 A61K49/04
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