| 发明名称 |
ANTI-MIF ANTIBODY CELL MIGRATION ASSAY |
| 摘要 |
The present invention pertains to a robust, precise and easy-to-use assay for potency of anti-MIF antibodies. In particular, the invention discloses an anti-MIF antibody-cell migration assay and respective method and kit. |
| 申请公布号 |
US2015309012(A1) |
申请公布日期 |
2015.10.29 |
| 申请号 |
US201314649509 |
申请日期 |
2013.12.05 |
| 申请人 |
BAXTER INTERNATIONAL INC. ;BAXTER HEALTHCARE SA |
发明人 |
Thiele Michael;Kerschbaumer Randolf |
| 分类号 |
G01N33/50;C07K16/40 |
主分类号 |
G01N33/50 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. Assay method for determining the potency of anti-MIF antibodies, wherein a cell migration is performed, wherein the assay method comprises the following steps:
providing cells which are capable of migration in a first part of a device, wherein the cells comprise MIF, adding the anti-(ox)MIF antibody to be determined, to a second part of the device, which is configured to be in a connection with the first part of the device which allows cell migration and diffusion, and calculating inhibition of migration. |
| 地址 |
Deerfield IL US |
