| 主权项 |
1. A process for producing an allergen extract comprising:
a) contacting a source material comprising with a liquid extraction agent to produce a mixture containing lipids dissolved in liquid phase and a solid phase consisting of source material residue comprising allergens and proteins, b) subjecting the mixture to a first separation step to isolate the source material residue, c) contacting the source material residue with an allergen extract agent to produce a mixture of allergens dissolved in liquid phase, and a solid phase consisting of non-allergenic residue, d) subjecting the mixture to a second separation step to isolate the allergens dissolved in liquid phase, to produce a crude allergen extract, e) subjecting the crude allergen extract to a low molecular fraction removal step to remove molecules having a molecular size of less than 3.5 kDa, and f) carrying out step e) until the allergen extract has conductivity of below 1000 μS/cm at 3-5° C. to obtain a purified native allergen extract. |
